Born 1962 in Hyogo Prefecture, Keisuke Yamaguchi graduated in 1985 from Musashino Art University. At the Exhibition of Modern Art in 1987 he won the award of the Gunma Prefectural Museum of Modern Art, and the Grand Prix in 1991. At the International Art Exhibition of 1988 he furthermore won the award of the Mie Prefectural Museum, as well as the price of the Tokyo National Museum of Modern Art in 1989.

While Yamaguchi initially worked with oil painting, but became interested into printmaking over the course of 1988, when he began to engage in large-format copperplate printing in particular. More recently, Yamaguchi has focused on paintings, three-dimensional works and installations that thematically center on nuclear energy and environmental issues. His “Cassette Plant” installations, using plants and flowers inserted into assemblages of audio cassette cases, contributed further to his rising recognition in the art world.